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mpiBLAST

mpiBLAST is a freely available, open-source, parallelization of NCBI BLAST. mpiBLAST segments the BLAST database and distributes it across cluster nodes, permitting BLAST queries to be processed on many nodes simultaneously. mpiBLAST is based on MPI and runs under Linux, Windows, and various varieties of Unix.
 
For more information see the mpiBlast homepage.