Hope College Biology

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Picture of Maria A. Burnatowska-Hledin Maria A. Burnatowska-Hledin Professor of Biology and Chemistry

Education

  • Physiology, McGill University, Ph.D., 1980
  • Physiology, McGill University, M.S., 1977
  • Biochemistry, McGill University, B.S., 1975

Research Interests

The action of vasopressin is essential for body fluid homeostasis and blood pressure regulation. Recently, we have cloned a vasopressin binding protein (VACM-1) from the kidney that mobilizes cytosolic free calcium in response to vasopressin. This protein shows no homology with known vasopressin receptors and represents a novel family of receptors. Thus, the research conducted in our laboratory is directed at characterizing this new protein and the role it may play in water reabsorption by the kidney and in blood pressure regulation. Students will work on individual projects relating to the ongoing research of the lab. They will learn new techniques in molecular biology and biochemistry including making cDNA libraries, PCR, cloning techniques, mutagenesis, DNA sequencing, mRNA, DNA and protein isolation and purification, electrophoresis, Northern, Western and Southern blotting, spectrophotometry, tissue culture, and intracellular ion measurements.

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Affiliations

  • American Physiological Society
  • American Association for the Advancement of Science
  • American Society of Biochemistry and Molecular Biology
  • American Society of Cell Biology
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Contact Details

Phone: 616-395-7764
Fax: 616-395-7125
Email: hledin@hope.edu
Office: Science Center 3061

Office Hours

Tuesdays 9:30-10:30
Wednesdays 9:00-10:00
By appointment